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D. Garrett Brown, June L. Round  Cell 

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1 Friends in Low Places: Intestinal Commensals Limit Colitis through Molecular Mimicry 
D. Garrett Brown, June L. Round  Cell  Volume 171, Issue 3, Pages (October 2017) DOI: /j.cell Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Mimetic Peptides from Commensal Bacteria Can Enforce Commensal-Host Interactions through Cytotoxic CD8+ T Cells Bacteroides-expressed BaclYL36–44, found in commensal Bacteroides, can draw IGRP-specific CD8+ T cells to the gastrointestinal tissue. This epitope influences a low-avidity interaction between CD11c+ antigen-presenting cells (APCs) and IGRP-specific CD8+ T cells. Killing of BaclYL expressing DCs occurs in a perforin-dependent manner, thereby leading to reduced colitis. Cell  , DOI: ( /j.cell ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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