1. Efficacy of Linaclotide for Patients With Chronic Constipation
Anthony J. Lembo, Caroline B. Kurtz, James E. MacDougall, B.J. Lavins, Mark G. Currie, Donald A. Fitch, Brenda I. Jeglinski, Jeffrey M. Johnston 
Gastroenterology 
Volume 138, Issue 3, Pages e1 (March 2010)
DOI: /j.gastro
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2. Supplementary Figure 1 Diagram of patient flow through study.
Gastroenterology  , e1DOI: ( /j.gastro )
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3. Figure 1
Effects of linaclotide on bowel function, including spontaneous bowel movements (SBM), complete spontaneous bowel movements (CSBM), straining, and stool consistency. BSFS, Bristol Stool Form Scale.
Gastroenterology  , e1DOI: ( /j.gastro )
Copyright © 2010 AGA Institute Terms and Conditions

4. Figure 2
Percentage of spontaneous bowel movements (SBM) and complete spontaneous bowel movement (CSBM) responders. CSBM and SBM responders were defined as a patient who, for 3 of the 4 treatment weeks, had a weekly CSBM (or SBM) rate ≥3 and an increase ≥1 relative to baseline.
Gastroenterology  , e1DOI: ( /j.gastro )
Copyright © 2010 AGA Institute Terms and Conditions

5. Figure 3
Effects of linaclotide on abdominal symptoms (discomfort and bloating), constipation severity, and global relief of constipation.
Gastroenterology  , e1DOI: ( /j.gastro )
Copyright © 2010 AGA Institute Terms and Conditions