Presentation is loading. Please wait.

Presentation is loading. Please wait.

Joseph H. Rapp, MD, Hobart W. Harris, MD, Robert L

Similar presentations


Presentation on theme: "Joseph H. Rapp, MD, Hobart W. Harris, MD, Robert L"— Presentation transcript:

1 Particle size distribution of lipoproteins from human atherosclerotic plaque: A preliminary report 
Joseph H. Rapp, MD, Hobart W. Harris, MD, Robert L. Hamilton, PhD, William C. Krupski, MD, Linda M. Reilly, MD, William K. Ehrenfeld, MD, Ronald J. Stoney, MD, Jerry Goldstone, MD, John P. Kane, MD, PhD  Journal of Vascular Surgery  Volume 9, Issue 1, Pages (January 1989) DOI: / (89)90222-X Copyright © 1989 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 1 Electron photomicrograph of lipoproteins recovered from aortic endarterectomy specimen by apo B selected-affinity immunosorption column and concentrated by pressure filtration. Note preponderance of intermediate-sized particles. (Original magnification × 180,000.) Journal of Vascular Surgery 1989 9, 81-88DOI: ( / (89)90222-X) Copyright © 1989 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 2 Particle distribution of the lipoproteins in Fig. 1.
Journal of Vascular Surgery 1989 9, 81-88DOI: ( / (89)90222-X) Copyright © 1989 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

4 Fig. 3 Electron micrograph of lipoproteins from another aortic endarterectomy specimen recovered by apo B selected-affinity immunosorption column and concentrated by pressure filtration. In this specimen there is a preponderance of LDL (175 to 250 nm), although intermediate-sized and VLDL-sized particles are also evident. Journal of Vascular Surgery 1989 9, 81-88DOI: ( / (89)90222-X) Copyright © 1989 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

5 Fig. 4 Particle distribution of the lipoproteins in Fig. 3.
Journal of Vascular Surgery 1989 9, 81-88DOI: ( / (89)90222-X) Copyright © 1989 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

6 Fig. 5 Summation graph of all plaque specimens. LDL-sized particles accounted for 56% of those counted, 36% were intermediate in size, and 8% were in the VLDL-size range. Journal of Vascular Surgery 1989 9, 81-88DOI: ( / (89)90222-X) Copyright © 1989 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

7 Fig. 6 Electron micrograph at a lower power shows a large field of lipoproteins recovered from a renal endarterectomy specimen by selected-affinity inmunosorption and concentrated by pressure filtration. The range of particles present in these atherosclerotic plaques is clearly shown. (Original magnification × 60,000.) Journal of Vascular Surgery 1989 9, 81-88DOI: ( / (89)90222-X) Copyright © 1989 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions


Download ppt "Joseph H. Rapp, MD, Hobart W. Harris, MD, Robert L"

Similar presentations


Ads by Google