1. Iron and noncontrast magnetic resonance T2
Iron and noncontrast magnetic resonance T2* as a marker of intraplaque iron in human atherosclerosis 
Marshall W. Winner, MD, Travis Sharkey-Toppen, MS, Xiaolan Zhang, PhD, Michael L. Pennell, PhD, Orlando P. Simonetti, PhD, Jay L. Zweier, MD, Patrick S. Vaccaro, MD, Subha V. Raman, MD 
Journal of Vascular Surgery 
Volume 61, Issue 6, Pages (June 2015)
DOI: /j.jvs
Copyright © 2015 Society for Vascular Surgery Terms and Conditions

2. Fig 1
Magnetic resonance gradient-echo images are acquired at multiple echo times to measure carotid artery T2* relaxation time. From left, echo times are 2.7 ms, 7.5 ms, 12.3 ms, 17.1 ms, and 22.4 ms. T2* is computed from the signal intensity decay over successive echo times within a region of interest encompassing the plaque.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2015 Society for Vascular Surgery Terms and Conditions

3. Fig 2
Ferritin levels were significantly higher in carotid artery atherosclerotic plaques compared with measurements obtained in control mammary arteries (P < .001). n = 46 atherosclerotic samples and n = 17 control samples.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2015 Society for Vascular Surgery Terms and Conditions

4. Fig 3
Oxidized low-density lipoprotein (LDL) levels were significantly higher in carotid plaques compared with measurements obtained in control mammary arteries (P < .001). n = 46 atherosclerotic samples and n = 17 control samples.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
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5. Fig 4
Hepcidin levels were significantly higher in carotid plaque samples compared with measurements obtained in control mammary artery samples (P = .03). n = 46 atherosclerotic samples and n = 10 control samples.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
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6. Fig 5
The range of insoluble iron levels was greater in carotid plaque samples compared with measurements obtained in control mammary artery samples; however, even after excluding an unusually high outlier in a control sample obtained from a 76-year-old individual, median values were similar (P = .55).
Journal of Vascular Surgery  , DOI: ( /j.jvs )
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7. Fig 6
Bland-Altman analysis demonstrated excellent interobserver agreement in carotid artery T2* measurements (r = .84; P < .001) and no significant bias (r = .22; P = .14), with an absolute mean difference of 0.45 ms and standard deviation of CI, Confidence interval.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2015 Society for Vascular Surgery Terms and Conditions

8. Fig 7
Ferritin levels did not significantly correlate with intraplaque T2* in patients with carotid artery atherosclerosis.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2015 Society for Vascular Surgery Terms and Conditions

9. Fig 8
In vivo T2* measured with noncontrast magnetic resonance imaging (MRI) in the atherosclerotic carotid artery wall was shorter than in the healthy artery wall of control subjects (P < .001). The error bars represent standard deviations.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2015 Society for Vascular Surgery Terms and Conditions