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Adipose and Hair Function: An aPPARent Connection
Nasif Islam, Luis A. Garza Journal of Investigative Dermatology Volume 138, Issue 3, Pages (March 2018) DOI: /j.jid Copyright © 2017 The Authors Terms and Conditions
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Figure 1 The model as proposed by Sardella et al. (2017). PPARγ is crucial for regulating adipogenesis, during which preadipocytes differentiate into mature adipocytes. Additionally, PPARγ promotes sebocyte maturation and proper hair follicle morphogenesis and maintenance of the pilosebaceous unit. Dysregulation or ablation of PPARγ signaling results in a temporal delay of hair follicle morphogenesis and and defective hair cycling. Journal of Investigative Dermatology , DOI: ( /j.jid ) Copyright © 2017 The Authors Terms and Conditions
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