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James C. Hurley, MBBS, DMedSci, MEpi, PhD  CHEST 

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Presentation on theme: "James C. Hurley, MBBS, DMedSci, MEpi, PhD  CHEST "— Presentation transcript:

1 Ventilator-Associated Pneumonia Prevention Methods Using Topical Antibiotics 
James C. Hurley, MBBS, DMedSci, MEpi, PhD  CHEST  Volume 146, Issue 4, Pages (October 2014) DOI: /chest Copyright © 2014 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Schematic of control and intervention patients receiving mechanical ventilation in an ICU. Color coding within horizontal arrows represent different colonizing flora, and circular arrows represent contextual effects resulting from cross-colonization. CHEST  , DOI: ( /chest ) Copyright © 2014 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Category-specific mean ventilator-associated pneumonia incidence and 95% CIs. A, Observational and control groups. B, Intervention groups. The dashed line shows the summary mean ventilator-associated pneumonia incidence derived from the observational studies. Note that the x-axis is a logit scale. NC = nonconcurrent; TA = (studies of) topical antibiotic. CHEST  , DOI: ( /chest ) Copyright © 2014 The American College of Chest Physicians Terms and Conditions

4 Figure 3 Scatter plots of ventilator-associated pneumonia incidence. A, Observational and control groups. B, Intervention groups. The center dashed line shows the summary mean ventilator-associated pneumonia incidence derived from the observational studies together with the 95% prediction intervals (right and left dashed lines). Note that the x-axis is a logit scale. See legend for expansion of abbreviations. CHEST  , DOI: ( /chest ) Copyright © 2014 The American College of Chest Physicians Terms and Conditions


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