1. Volume 78, Issue 2, Pages 256-268 (April 2013)
GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease 
Carlos Cruchaga, John S.K. Kauwe, Oscar Harari, Sheng Chih Jin, Yefei Cai, Celeste M. Karch, Bruno A. Benitez, Amanda T. Jeng, Tara Skorupa, David Carrell, Sarah Bertelsen, Matthew Bailey, David McKean, Joshua M. Shulman, Philip L. De Jager, Lori Chibnik, David A. Bennett, Steve E. Arnold, Denise Harold, Rebecca Sims, Amy Gerrish, Julie Williams, Vivianna M. Van Deerlin, Virginia M.-Y. Lee, Leslie M. Shaw, John Q. Trojanowski, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak-Vance, Lindsay A. Farrer, Gerard D. Schellenberg, Elaine R. Peskind, Douglas Galasko, Anne M. Fagan, David M. Holtzman, John C. Morris, Alison M. Goate 
Neuron 
Volume 78, Issue 2, Pages (April 2013)
DOI: /j.neuron
Copyright © 2013 Elsevier Inc. Terms and Conditions

2. Figure 1
Genome-wide Signal Intensity (Manhattan) Plots Showing the Individual p Values (Based on Fixed-Effects Meta-analysis) against Genomic Position
The results for the association of CSF tau (top) and ptau (bottom) levels with 5,815,690 SNPs are shown. Within each chromosome, shown on the x axis, the results are plotted left to right from the p-terminal end. Horizontal dashed lines indicate p value thresholds of 1 × 10−5 and 5 × 10−8 (genome-wide significance).
Neuron  , DOI: ( /j.neuron )
Copyright © 2013 Elsevier Inc. Terms and Conditions

3. Figure 2
Regional Plots for Associations with CSF Tau and Ptau at Genome-wide Significance
Plots are centered on the most significant SNP at a given locus along with the combined-analysis results for SNPs in the region surrounding it (typically ± 400 kb). Symbols are colored according to the LD of the SNP with the top SNP. The light blue line represents the estimated recombination rate. Gene annotations are shown as dark green line. See also Tables S5 and S6.
Neuron  , DOI: ( /j.neuron )
Copyright © 2013 Elsevier Inc. Terms and Conditions