1. Pulmonary 1, Case 6
56-year-old man with progressive dyspnea and bilateral infiltrates in lung.

2. Identify the organ
Describe the gross morphologic changes
Diagnosis?

3. Idiopathic pulmonary fibrosis
Cut surface of lung with fibrosis and anthracosis

4. Compare to normal cut surface of lung

5. Identify the organ
Describe the gross morphologic changes
Diagnosis?

6. The cut surface of the lung reveals a "honeycomb" pattern of fibrosis.
Pulmonary fibrosis
The cut surface of the lung reveals a "honeycomb" pattern of fibrosis.
The large air spaces are accentuated by the thick walls of fibrous tissue.

8. Interstitial
fibrosis
Fibrous tissue
replacing normal
lung parenchyma
Large airspaces separated by
bands of fibrous tissue

10. Fibrosis
Alveolus lined by reactive pneumocytes