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Upper extremity ischemia treated with tissue repair cells from adult bone marrow  Anthony J. Comerota, MD, FACS, FACC, RVT, Angie Link, RN, BSN, Judy Douville,

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Presentation on theme: "Upper extremity ischemia treated with tissue repair cells from adult bone marrow  Anthony J. Comerota, MD, FACS, FACC, RVT, Angie Link, RN, BSN, Judy Douville,"— Presentation transcript:

1 Upper extremity ischemia treated with tissue repair cells from adult bone marrow 
Anthony J. Comerota, MD, FACS, FACC, RVT, Angie Link, RN, BSN, Judy Douville, MA, Elmar R. Burchardt, MD, PhD  Journal of Vascular Surgery  Volume 52, Issue 3, Pages (September 2010) DOI: /j.jvs Copyright © 2010 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Photograph of hands at presentation. Patient underwent prior amputation of right and left index fingers and left ring finger. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Photoplethysmographic waveforms of fingers of left hand at (A) initial presentation (motion artifact), (B) 1 month, (C) 3 months, and (D) 12 months after treatment. Right hand waveforms are similar. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Digital subtraction arteriogram of both upper extremities demonstrated that all arteries to and including the brachial arteries were normal. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

5 Fig 4 Bilateral arteriography showing severe occlusive disease of the distal radial ulnar and interosseus arteries bilaterally and small vessel disease of both hands. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

6 Fig 5 Laser Doppler imaging of patient 6 months after treatment. (A) Note “hot spots” at sites of injection, specifically thenar and hypothenar eminences and all web spaces. The specific injection sites are indicated in the (B) pretreatment photograph of the patient's hands. Laser Doppler image courtesy of Perimed AB, Stockholm. Sweden. Taken with PeriScan PIM3 System Laser Doppler Blood Perfusion Imager. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

7 Fig 6 Photograph of hands at 1 year showing improved perfusion and healing of all amputation sites. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions


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