Presentation is loading. Please wait.

Presentation is loading. Please wait.

Basophil activation test discriminates between allergy and tolerance in peanut- sensitized children  Alexandra F. Santos, MD, MSc, Abdel Douiri, PhD, Natalia.

Published byVerawati Setiabudi Modified over 5 years ago

Similar presentations

Presentation on theme: "Basophil activation test discriminates between allergy and tolerance in peanut- sensitized children  Alexandra F. Santos, MD, MSc, Abdel Douiri, PhD, Natalia."— Presentation transcript:

1 Basophil activation test discriminates between allergy and tolerance in peanut- sensitized children 
Alexandra F. Santos, MD, MSc, Abdel Douiri, PhD, Natalia Bécares, BSc, Shih-Ying Wu, MSc, Alick Stephens, PhD, Suzana Radulovic, MD, Susan M.H. Chan, MD, Adam T. Fox, MD, George Du Toit, MD, Victor Turcanu, PhD, Gideon Lack, MD, FRCPCH  Journal of Allergy and Clinical Immunology  Volume 134, Issue 3, Pages (September 2014) DOI: /j.jaci Copyright © Terms and Conditions

2 Fig 1 BAT to peanut in PA (n = 42, A), PS (n = 31, B), and NA (n = 19, C) children. The P value refers to the comparison of the median %CD63+ basophils at selected doses between PA and PS patients: ***P < .001, **P < .01, and ns, nonsignificant. 0 represents the negative control, and anti-IgE and fMLP are the positive controls. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © Terms and Conditions

3 Fig 2 ROC curves for BAT (red), SPT (blue), P-sIgE (green), and sIgE to Ara h 2 (orange) for the whole study population (n = 92) (A) and children with equivocal history, SPT, and sIgE to peanut and its components (n = 39) (B). For BAT, the average between %CD63+ basophils at 10 and 100 ng/mL of peanut extract was considered. For area under the ROC curves for different tests in the 2 study populations, see Table E5. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © Terms and Conditions

Download ppt "Basophil activation test discriminates between allergy and tolerance in peanut- sensitized children  Alexandra F. Santos, MD, MSc, Abdel Douiri, PhD, Natalia."

Similar presentations

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,
A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada Moshe Ben-Shoshan, MD, Daniel W. Harrington, MA,

A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada Moshe Ben-Shoshan, MD, Daniel W. Harrington, MA,
Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study George Du Toit, MBBCh, FRCPCH, Graham.

Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study George Du Toit, MBBCh, FRCPCH, Graham.
Peanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivity  Abena S. Amoah, MSc, Benedicta.

Peanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivity  Abena S. Amoah, MSc, Benedicta.
Skin prick test responses and allergen-specific IgE levels as predictors of peanut, egg, and sesame allergy in infants  Rachel L. Peters, MPH, Katrina.

Skin prick test responses and allergen-specific IgE levels as predictors of peanut, egg, and sesame allergy in infants  Rachel L. Peters, MPH, Katrina.
Diagnosing peanut allergy with skin prick and specific IgE testing

Diagnosing peanut allergy with skin prick and specific IgE testing
The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy  Jennifer M. Maloney, MD, Magnus Rudengren, BSc, Staffan.

The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy  Jennifer M. Maloney, MD, Magnus Rudengren, BSc, Staffan.
Margaretha A. Faber, MD, Vito Sabato, MD, Chris H

Margaretha A. Faber, MD, Vito Sabato, MD, Chris H
Distribution of peanut protein in the home environment

Distribution of peanut protein in the home environment
Role of the basophil activation test in the diagnosis of local allergic rhinitis  Enrique Gómez, PhD, Paloma Campo, MD, PhD, Carmen Rondón, MD, PhD, Esther.

Role of the basophil activation test in the diagnosis of local allergic rhinitis  Enrique Gómez, PhD, Paloma Campo, MD, PhD, Carmen Rondón, MD, PhD, Esther.
Ibrutinib, a Bruton’s tyrosine kinase inhibitor used for treatment of lymphoproliferative disorders, eliminates both aeroallergen skin test and basophil.

Ibrutinib, a Bruton’s tyrosine kinase inhibitor used for treatment of lymphoproliferative disorders, eliminates both aeroallergen skin test and basophil.
Making the Most of In Vitro Tests to Diagnose Food Allergy

Making the Most of In Vitro Tests to Diagnose Food Allergy
A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada  Moshe Ben-Shoshan, MD, Daniel W. Harrington, MA,

A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada  Moshe Ben-Shoshan, MD, Daniel W. Harrington, MA,
Does atopic dermatitis cause food allergy? A systematic review

Does atopic dermatitis cause food allergy? A systematic review
Peanut oleosins associated with severe peanut allergy—importance of lipophilic allergens for comprehensive allergy diagnostics  Christian Schwager, Dipl.

Peanut oleosins associated with severe peanut allergy—importance of lipophilic allergens for comprehensive allergy diagnostics  Christian Schwager, Dipl.
Is the prevalence of peanut allergy increasing

Is the prevalence of peanut allergy increasing
Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort 

Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort 
Children with allergic and nonallergic rhinitis have a similar risk of asthma  Bo Lund Krogsgaard Chawes, MD, Klaus Bønnelykke, MD, PhD, Eskil Kreiner-Møller,

Children with allergic and nonallergic rhinitis have a similar risk of asthma  Bo Lund Krogsgaard Chawes, MD, Klaus Bønnelykke, MD, PhD, Eskil Kreiner-Møller,
Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort 

Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort 
Prevention of food allergy

Prevention of food allergy

Similar presentations

Ads by Google