1. Cross CHAART Working Groups
A Proposal and an Invitation

2. Why Form Cross CHAART Groups?
To keep the meeting momentum going
Share expertise
Agree on metrics
Share best practices
Pool data
Be more than the sum of our parts
Stay alive in times of tough funding

3. Why Graft off VACS Rather Than Start Fresh?
Established administrative support system
Productive, collaborative groups that welcome new members
Can focus on creating new groups for domains not already covered, e.g….
PEth
Woman’s Health Workgroup

4. A Two Part Invitation
Part 1. A CHAART-Wide Invitation to Join Existing Working Groups
Part 2. An Invitation to Propose New Working Groups

5. Part 1. An Invitation to Join Existing Working Groups

6. Cores Alcohol and Behavior Change (David Fiellin)
Biostatistics (Jan Tate)
Cancer (Robert Dubrow)
Cardiovascular (Matt Freiberg)
Informatics (Cindy Brandt)
Liver (Vin Lore and Jan Tate)
Pulmonary (Kristina Crothers)
Translational (Charles Rinaldo and Matt Freiberg)

7. Workgroups ART (Neel Gandhi, Jan Tate)
Endocrine/Bone (Julie Womack, Barb Gulanski)
HSR&D (Kathy McGinnis, Emily Wang)
Kidney (Chirag Parikh)
Mental Health (Joe Goulet)
Opioids (Jen Edelman)
Physical Function (Kris Ann Oursler, Kathleen Akgun)
Polypharmacy (Jen Edelman)
Uniform Services (David Rimland, Brian Agan)
VACS Index (Amy Justice, Jan Tate)

8. Current Cross CHAART Collaboration
Jeffrey Samet, Bob Cook, Judy Hahn, Brandon Marshall, and Don Operario are members of Alcohol and Behavior Change
Matthew Freiberg, a PI in URBAN ARCH, Directs CVD and Translational Cores
Heidi Crane is a member of the CVD Core

9. Part 2. An Invitation to Propose Cross CHAART Initatives

10. Let’s Start With 2 Projects
PEth (Judy Hahn already discussed)
White Paper: “Alcohol and HIV in the Era of ART”

11. Alcohol and HIV in the Era of ART
What have we established?
Harmful alcohol use is associated with HIV transmission and progression
HIV increases susceptibility to harm from alcohol
What do we still need to do?
Demonstrate that we can definitively mitigate these harms through intervention
What is needed to accomplish this task?
Better measures of exposure (not self report)
Harder endpoints (not just change in alcohol)

12. Next Steps Judy will draft a proposal for the PEth analyses
I will draft an outline of the White Paper
Consortia Directors will appoint representatives to participate in each of these projects
At least one, not more than two for PEth
At least one, not more than three for white paper
Kendall Bryant, as NIAAA rep, gets a wild card
Angela will coordinate conference calls