1. Chemical encapsulation of rocuronium by synthetic cyclodextrin derivatives: reversal of neuromuscular block in anaesthetized Rhesus monkeys† 
H.D. de Boer, J van Egmond, F van de Pol, A Bom, L.H.D.J. Booij 
British Journal of Anaesthesia 
Volume 96, Issue 2, Pages (February 2006)
DOI: /bja/aei306
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

2. Fig 1
(a) Time course of the experiments (A) equilibration, (B) steady 90% block, (C, D) spontaneous recovery, (E) steady 90% block, (F) recovery with one of the test drugs, and (G) finally a period of evaluation of recurarization. (b) Comparison of spontaneous recovery of rocuronium-induced neuromuscular block with recovery in the presence of the test drug (in this case 0.5 mg kg−1 of Org 25969). Here the two recovery traces are depicted on top of one another.
British Journal of Anaesthesia  , DOI: ( /bja/aei306)
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

3. Fig 2
Course of neuromuscular recovery for spontaneous vs either one of the nine cyclodextrin derivatives or the neostigmine/atropine combination (neo/atro). Note: The values for spontaneous recovery depicted are means from all 38 experiments. Note that only Org and Org (at either of two dosages) provide faster recovery than the neostigmine/atropine combination.
British Journal of Anaesthesia  , DOI: ( /bja/aei306)
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

4. Fig 3
Typical example of the absence of effect of cyclodextrin on circulatory variables. Here, the most efficiently reversing cyclodextrin Org is injected at time=0 at the highest dose (1 mg kg−1). Spontaneous variation in pressures and HR during 1 h of monitoring are larger than the change because of injection at time=0. (SAP, systolic arterial pressure; MAP, mean arterial pressure; DAP, diastolic arterial pressure.)
British Journal of Anaesthesia  , DOI: ( /bja/aei306)
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions