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Osteoarthritis and Cartilage
Automatic 3D Selection, Segmentation, and Analysis of Human Articular Cartilage Chondrons from Micro-computed Tomography in vitro I. Kestilä, J.P. Thevenot, M.A. Finnilä, S.S. Karhula, I. Hadjab, S. Kauppinen, M. Garon, E. Quenneville, L. Rieppo, K.P. Pritzker, M.D. Buschmann, H.J. Nieminen, S. Saarakkala Osteoarthritis and Cartilage Volume 25, (April 2017) DOI: /j.joca Copyright © Terms and Conditions
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Figure 1. Top row: The average chondron volumes grouped by the OARSI histological grades (0–1.0 & 3.0–3.5) in three AC zones (0–10%, 10–40%, 40–100% from the AC surface). All the well segmented chondrons, chondrons containing a single cell, and chondrons containing a cluster were studied separately. *: p value 0.01 to 0.05, **: p value to Bottom row: Left; A–D: Example images of three orthogonal views from the manual segmentation verification. A = a well segmented cluster, B = a poorly segmented cluster, C = a well segmented single cell, D = a poorly segmented single cell. Right; 3D models of the segmented chondrons from representative OARSI 0 and OARSI 3 samples. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © Terms and Conditions
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