Presentation is loading. Please wait.

Presentation is loading. Please wait.

Figure 1 Transmission of pain by NGF

Published byJunior Hardy Modified over 5 years ago

Similar presentations

Presentation on theme: "Figure 1 Transmission of pain by NGF"— Presentation transcript:

1 Figure 1 Transmission of pain by NGF
Figure 1 | Transmission of pain by NGF. The neurotrophin β-nerve growth factor (NGF) is released upon injury and causes pain by activating its receptor (TrkA) on nociceptors and mast cells (which causes the release of inflammatory mediators such as histamine), leading to transmission of pain signals from the periphery to the spinal cord and brain via the dorsal ganglion. Inhibitors of NGF have shown promise in clinical trials of musculoskeletal pain. Lane, N. E. & Corr, M. (2017) Anti-NGF treatments for pain — two steps forward, one step back? Nat. Rev. Rheumatol. doi: /nrrheum

Download ppt "Figure 1 Transmission of pain by NGF"

Similar presentations

Bioassay with cultured ganglia. Transport of NGF.

Bioassay with cultured ganglia. Transport of NGF.
Chapter 83: Bone Cancer and Pain Mary Ann C. Sabino and Denis R. Clohisy.

Chapter 83: Bone Cancer and Pain Mary Ann C. Sabino and Denis R. Clohisy.
Figure 23.1 Growth cones guide axons in the developing nervous system.

Figure 23.1 Growth cones guide axons in the developing nervous system.
Assessment StatementsObj. E1.1 Define the terms stimulus, response and reflex. 1 E1.2 Explain the role of receptors, sensory neurons, relay neurons, motor.

Assessment StatementsObj. E1.1 Define the terms stimulus, response and reflex. 1 E1.2 Explain the role of receptors, sensory neurons, relay neurons, motor.
Stimulus & Response Assessment Statements Obj. E1.1 1 E1.2 3 E1.3 E1.4

Stimulus & Response Assessment Statements Obj. E1.1 1 E1.2 3 E1.3 E1.4
Figure 1 Simplified scheme of TGFβ signalling

Figure 1 Simplified scheme of TGFβ signalling
1 Chapter 12 Central Nervous System Spinal Cord

1 Chapter 12 Central Nervous System Spinal Cord
MONOCLONAL ANTIBODIES AGAINST NERVE GROWTH FACTOR IN PAIN MANAGENT

MONOCLONAL ANTIBODIES AGAINST NERVE GROWTH FACTOR IN PAIN MANAGENT
W5D3H3: Sensory Receptors

W5D3H3: Sensory Receptors
Fig. 2. The sympathetic nervous system (SNS) and pain

Fig. 2. The sympathetic nervous system (SNS) and pain
Pain Modulation Pain Transmission

Pain Modulation Pain Transmission
Neurons.

Neurons.
Echalk response experiment

Echalk response experiment
of different experimental arthritis models

of different experimental arthritis models
Figure 2 Functional model of enthesitis

Figure 2 Functional model of enthesitis
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Structure of TNF antagonists

Figure 1 Structure of TNF antagonists
Figure 1 Induction of immune tolerance

Figure 1 Induction of immune tolerance
Nat. Rev. Neurol. doi: /nrneurol

Nat. Rev. Neurol. doi: /nrneurol

Similar presentations

Ads by Google