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Key Discoveries in Melanocyte Development

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1 Key Discoveries in Melanocyte Development
Akinori Kawakami, David E. Fisher  Journal of Investigative Dermatology  Volume 131, Pages E2-E4 (November 2011) DOI: /skinbio Copyright © 2011 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Migratory pathways of chick trunk neural crest cells, adapted from Cell 2009; 139:366–379. Region 1: Melanoblasts (Mitf/Sox10 positive cells) migrating within the dorsolateral pathway (the ‘‘classic’’ melanoblast migration route). 2a: Melanoblasts located near ventral spinal nerves. 2b: Melanoblasts along nerves of dorsal rami. nt, neural tube; drg, dorsal root ganglion; dm, dermamyotome; dr, dorsal ramus; snv, ventral branch of the spinal nerve; HH, Hamburger Hamilton stage. Journal of Investigative Dermatology  , E2-E4DOI: ( /skinbio ) Copyright © 2011 The Society for Investigative Dermatology, Inc Terms and Conditions


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