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Frank C. Detterbeck, MD, Andrew G

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1 The Masaoka-Koga Stage Classification for Thymic Malignancies: Clarification and Definition of Terms 
Frank C. Detterbeck, MD, Andrew G. Nicholson, MD, Kazuya Kondo, MD, PhD, Paul Van Schil, MD, PhD, Cesar Moran, MD  Journal of Thoracic Oncology  Volume 6, Issue 7, Pages S1710-S1716 (July 2011) DOI: /JTO.0b013e31821e8cff Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Penetrations within the fibrous capsule of a thymoma are classified as noninvasive, although they do (partially) invade the capsule. Absence of a capsule by itself does not constitute invasion. Journal of Thoracic Oncology 2011 6, S1710-S1716DOI: ( /JTO.0b013e31821e8cff) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Schematic diagram of transcapsular invasion included in stage IIa. Journal of Thoracic Oncology 2011 6, S1710-S1716DOI: ( /JTO.0b013e31821e8cff) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 A and B, Types of invasion included in stage IIb. This may range from (A) a single area of localized invasion to (B) more extensive involvement of the mediastinal fat without pleural or pericardial involvement. Journal of Thoracic Oncology 2011 6, S1710-S1716DOI: ( /JTO.0b013e31821e8cff) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 4 A and B, Types of invasion included in stage III. A, Schematic diagram of involvement of the mediastinal pleura or partial involvement of the pericardium, or vessels. B, Penetration through the pericardium, the visceral pleura, or into the phrenic nerve. Journal of Thoracic Oncology 2011 6, S1710-S1716DOI: ( /JTO.0b013e31821e8cff) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

6 FIGURE 5 A and B, Separate foci of tumor included in stage IV. A, Separate nodule on the pleural or pericardial surfaces classified as IVa. B, Involvement of nodal sites, extrathoracic sites, or parenchymal lung nodules. Journal of Thoracic Oncology 2011 6, S1710-S1716DOI: ( /JTO.0b013e31821e8cff) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

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