1. TargetDB and PEPCDB •

2. Target Registration Database TargetDB • http://targetdb.pdb.org/
Targets downloadable in XML (~43,000 targets)
Targets downloaded from 17 worldwide centers weekly
Target search by:
Sequence (FASTA), project target ID, project site, status (selected, cloned, expressed, … in PDB), update date, protein name, source organism
Report output in HTML, FASTA, and XML
Integrates PDB entry sequences (~53,000 sequences)
Includes PDB pre-release sequence data
Provides links to related project sequence databases
Summary reports of target and project progress
3-Tier architecture (Apache/Tomcat/MySQL) 29

4. TargetDB - Search Options
Project target ID
Date of status change
Protein and source names
Report
formats

5. TargetDB - Status Search
Status codes

6. TargetDB - Site Search
Site list

7. TargetDB - Content Options
Sequence
collections

8. TargetDB - Sequence Search
and search criterion

9. TargetDB - HTML Report Links to project and sequence databases
Link to PDB Structure Explorer report

10. TargetDB - Site Status Summaries

11. TargetDB - Site Status Summaries
Project target ID
Report period
Project site

12. TargetDB - Site Status Reports
Expand report to target list

13. TargetDB - Site Target Progress Reports

14. Protein Expression Purification and Crystallization Database PEPCDB
Extends content of TargetDB with: status history, stop conditions, reusable text protocols (cloning, expression, purification, crystallization, and NMR), protocol extensions, contact information
Today - prototype database and query interface with data from CESG and SESG loaded
Extends TargetDB search with: stop status, protocol type, protocol identifier, and protocol text
Report output in HTML, FASTA, and XML
Integrates PDB entry and pre-release sequences
Reports provide links to status history, related protocols, project, sequence and domain databases
3-Tier architecture (Apache/Tomcat/IBM DB2) 29

15. PEPCDB - Search Options

16. PEPCDB - Search Options
Stop status options

17. PEPCDB - Search Options
Protocol search options

18. PEPCDB - HTML Reports Link to status history Links to domain sites
Links to project and sequence sites
Links to protocol descriptions

19. PEPCDB - Status History Report

20. PEPCDB - Links to Domain Databases

21. PEPCDB - Links to Protocol Descriptions