1. Reappearance of myocytes in ovine infarcts produced by six hours of complete ischemia followed by reperfusion 
Frank W Bowen, MD, Takashi Hattori, MD, Nanveet Narula, MD, Ivan S Salgo, MD, Theodore Plappert, Martin G St. John Sutton, MBBS, L.Henry Edmunds, MD 
The Annals of Thoracic Surgery 
Volume 71, Issue 6, Pages (June 2001)
DOI: /S (01)02642-X

2. Fig 1 Infarct sampling sites for measurements of collagen types.
The Annals of Thoracic Surgery  , DOI: ( /S (01)02642-X)

3. Fig 2
Long axis, end systolic echocardiograms. (A) Before infarction. (B) Contrast echocardiogram during ischemia (arrows indicate margins). (C) Contrast echocardiogram after reperfusion. (D–F) Contrast echocardiograms at the 12th week: (D) nonperfused; (E) 1-hour ischemia; (F) 6-hour ischemia.
The Annals of Thoracic Surgery  , DOI: ( /S (01)02642-X)

4. Fig 3
(A) Serial left ventricular end-systolic volumes. (B) Serial changes in left ventricular stroke work. (■ = Nonperfused sheep; • = 1-hour ischemia; ▾ = 6-hour ischemia. See Table 2 for statistics.)
The Annals of Thoracic Surgery  , DOI: ( /S (01)02642-X)

5. Fig 4
Above, longitudinal cut specimens at the 12th week. Below, histologic sections (×1 before 25% reduction) of infarct edges (Masson’s trichrome). Myocytes stain red-brown. (A,D) nonperfused; (B,E) 1-hour ischemia; (C-F) 6-hour ischemia. Arrows mark infarction edges.
The Annals of Thoracic Surgery  , DOI: ( /S (01)02642-X)

6. Fig 5
Sections of myocardium stained with Masson’s trichrome from a sheep after 6 hours of ischemia and 2 (A) and 12 (B) weeks of reperfusion. The epicardium is uppermost. After 2 weeks all myocytes in the infarct are necrotic (bluish gray). No viable myocytes are present in the epicardium. Early fibrosis and granulation tissue is visible. After 12 weeks of reperfusion, a band of viable myocytes (stained red) is present in the epicardium. Scar tissue is stained blue (×10 before 10% reduction).
The Annals of Thoracic Surgery  , DOI: ( /S (01)02642-X)

7. Fig 6
Myocyte ultrastructure in a sheep after 6 hours of ischemia and 2 (A and B) and 12 weeks (C) of reperfusion. At 2 weeks (A), occasional viable myocytes are visible in the subepicardial region of the infarct. Viable myocytes are smaller. Cellular cytoplasm contains mitochondria, sarcoplasmic reticulum, and thick filaments with z-bands. The thick filaments with z-bands are seen predominantly at the periphery of the cell (×10,500 before 17% reduction). (B) At higher magnification mitochondria and filaments with z-bands are visible (×12,000 before 17% reduction). (C) Electron micrograph of an epicardial myocyte from a sheep after 6 hours of ischemia and 12 weeks reperfusion. The myocyte contains numerous mitochondria and myofilaments (×4,500 before 17% reduction).
The Annals of Thoracic Surgery  , DOI: ( /S (01)02642-X)

8. Fig 7
(A) Ratios of collagen types I/III (mean ± SE). (B) Hydroxyproline content (n = 5 for each group). p < 0.05 for nonperfused versus both reperfused groups for collagen ratios and hydroxyproline.
The Annals of Thoracic Surgery  , DOI: ( /S (01)02642-X)