1. Imatinib decreases endometrial stromal cell transmesothial migration and proliferation in the extracellular matrix of modeled peritoneum 
Jason S. Griffith, M.D., Peter A. Binkley, B.A., Namir B. Kirma, Ph.D., Robert S. Schenken, M.D., Craig A. Witz, M.D., Rajeshwar R. Tekmal, Ph.D. 
Fertility and Sterility 
Volume 94, Issue 7, Pages (December 2010)
DOI: /j.fertnstert
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Attachment assay. Using ESCs from five different women, there was no difference in attachment of ESC's to PMC's after imatinib treatment of 10 μM for 7 days.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Imatinib treatment of ESC's resulted in reduction of proliferation in 3-D collagen I matrix. Individual data points are shown. The control values for invasion were set to unity. The horizontal line represents the average percentage of invasion versus control. Treatment with 0.5 μM, 2 μM, and 10 μM average proliferation by 30%, 72%, and 76% respectively versus control. Treatment with 0.1 μM did not statistically significantly reduce proliferation (∗P<.05).
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

4. Figure 3
Treatment of ESCs with imatinib decreased invasion in modeled peritoneum. Individual data points are shown. The control values for proliferation were set to unity. The horizontal line represents the average percentage of proliferation versus control. Treatment with 5 μM decreased average invasion by 30%. Treatment with 10 μM resulted a 73% decrease in mean rate of invasion. No difference in invasion was seen at the 2 μM dose (∗P<.05).
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

5. Figure 4
Fluorescent ESCs invading through modeled peritoneum (final magnification = ×250). (A) Control ESCs. (B) Imatinib treated (10 μM) ESCs.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions