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Experimental Hematology

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Presentation on theme: "Experimental Hematology"— Presentation transcript:

1 Experimental Hematology
Erratum  Experimental Hematology  Volume 30, Issue 5, (May 2002) DOI: /S X(02)

2 Figure 1 NFκB-dependent signaling pathways. NFκB is activated by many extracellular stimuli, including many different pathogens, cytokines, stress signals, and growth factors. Once NFκB is fully activated, it helps to regulate various genes in different target cells that have important roles in immune responses, stress responses, cell survival, and development. Experimental Hematology  , DOI: ( /S X(02) )

3 Figure 2 TNF and IL-1 signaling pathways. While both TNF and IL-1 induce the activation of NFκB and JNK, TNF also induces apoptosis. NFκB activation protects cells from TNF-induced apoptosis by upregulating antiapoptotic genes, including TRAF1, TRAF2, IAP1, IAP2, and FLIP. Experimental Hematology  , DOI: ( /S X(02) )

4 Figure 3 Ligand specificities of Toll-like receptors.
Experimental Hematology  , DOI: ( /S X(02) )


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