1. Fine Mapping of the Split-Hand/Split-Foot Locus (SHFM3) at 10q24: Evidence for Anticipation and Segregation Distortion 
Rýdvan S. Özen, Bora E. Baysal, Bernie Devlin, Joan E. Farr, Michael Gorry, Garth D. Ehrlich, Charles W. Richard 
The American Journal of Human Genetics 
Volume 64, Issue 6, Pages (June 1999)
DOI: /302403
Copyright © 1999 The American Society of Human Genetics Terms and Conditions

2. Figure 1
Turkish SHFM pedigree. Blackened symbols represent clinically affected individuals, and unblackened symbols represent unaffected individuals. Numbers within symbols represent the number of unaffected offspring and their unaffected descendants, collapsed for clarity and space limitations.
The American Journal of Human Genetics  , DOI: ( /302403)
Copyright © 1999 The American Society of Human Genetics Terms and Conditions

3. Figure 2 Summary of clinical findings in affected relatives with SHFM
The American Journal of Human Genetics  , DOI: ( /302403)
Copyright © 1999 The American Society of Human Genetics Terms and Conditions

4. Figure 3
Anticipation in SHFM3. Three-generational worsening of SHFM phenotype. Numbers refer to pedigree member numbering shown in figure 1.
The American Journal of Human Genetics  , DOI: ( /302403)
Copyright © 1999 The American Society of Human Genetics Terms and Conditions

5. Figure 4
Genetic crossover events in the Turkish SHFM family and a genetic map of selected 10q q24.3 STRP markers are shown. Genetic map distances are taken from the Whitehead/MIT Center for Genome Research. The dark gray bars represent the SHFM3 disease haplotype. Above the bar, the pedigree number and affection status are shown. A = affected, and U = unaffected. Alleles within the lightly shaded bar of individual 58 were uninformative.
The American Journal of Human Genetics  , DOI: ( /302403)
Copyright © 1999 The American Society of Human Genetics Terms and Conditions