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Restriction of Zika Virus by Host Innate Immunity

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1 Restriction of Zika Virus by Host Innate Immunity
Xuping Xie, Chao Shan, Pei-Yong Shi  Cell Host & Microbe  Volume 19, Issue 5, Pages (May 2016) DOI: /j.chom Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Restriction of ZIKV Infection by Host Innate Immunity
(A) Ifnar1−/− mice and Irf3−/− Irf5−/− Irf7−/− TKO mice developed neurological disease and succumbed to ZIKV infection. (B) Human placental trophoblasts produce IFNλ1 to protect trophoblast and non-trophoblast cells from ZIKV infection. Cell Host & Microbe  , DOI: ( /j.chom ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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