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Serum hepatitis B core-related antigen is more accurate than hepatitis B surface antigen to identify inactive carriers, regardless of hepatitis B virus.

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Presentation on theme: "Serum hepatitis B core-related antigen is more accurate than hepatitis B surface antigen to identify inactive carriers, regardless of hepatitis B virus."— Presentation transcript:

1 Serum hepatitis B core-related antigen is more accurate than hepatitis B surface antigen to identify inactive carriers, regardless of hepatitis B virus genotype  M. Riveiro-Barciela, M. Bes, F. Rodríguez-Frías, D. Tabernero, A. Ruiz, R. Casillas, J. Vidal-González, M. Homs, L. Nieto, S. Sauleda, R. Esteban, M. Buti  Clinical Microbiology and Infection  Volume 23, Issue 11, Pages (November 2017) DOI: /j.cmi Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Comparison of mean hepatitis B surface antigen (HBsAg) and hepatitis B core-related antigen (HBcrAg) levels between inactive carriers and patients with hepatitis B virus (HBV) activity showed statistical differences in patients infected by genotype A (HBsAg and HBcrAg) and D (HBsAg), but not in those with genotypes E, F or H infection. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Correlations between hepatitis B virus (HBV) DNA and both hepatitis B surface antigen (HBsAg) (a) and hepatitis B core-related antigen (HBcrAg) (b) reached statistical significance. Independent analysis by each genotype showed that correlations were only present in patients infected by genotype A (HBsAg and HBcrAg) and D (only HBsAg). Moderate correlations between HBsAg and HBcrAg levels (c) were found in genotype A and D patients. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

4 Fig. 2 Correlations between hepatitis B virus (HBV) DNA and both hepatitis B surface antigen (HBsAg) (a) and hepatitis B core-related antigen (HBcrAg) (b) reached statistical significance. Independent analysis by each genotype showed that correlations were only present in patients infected by genotype A (HBsAg and HBcrAg) and D (only HBsAg). Moderate correlations between HBsAg and HBcrAg levels (c) were found in genotype A and D patients. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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