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Phase 2 Study of Pemetrexed and Itraconazole as Second-Line Therapy for Metastatic Nonsquamous Non–Small-Cell Lung Cancer  Charles M. Rudin, MD, PhD,

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Presentation on theme: "Phase 2 Study of Pemetrexed and Itraconazole as Second-Line Therapy for Metastatic Nonsquamous Non–Small-Cell Lung Cancer  Charles M. Rudin, MD, PhD,"— Presentation transcript:

1 Phase 2 Study of Pemetrexed and Itraconazole as Second-Line Therapy for Metastatic Nonsquamous Non–Small-Cell Lung Cancer  Charles M. Rudin, MD, PhD, Julie R. Brahmer, MD, Rosalyn A. Juergens, MD, PhD, Christine L. Hann, MD, PhD, David S. Ettinger, MD, Rosa Sebree, BS, Ruth Smith, RN, Blake T. Aftab, PhD, Peng Huang, PhD, Jun O. Liu, PhD  Journal of Thoracic Oncology  Volume 8, Issue 5, Pages (May 2013) DOI: /JTO.0b013e31828c3950 Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Duration of therapy on study. Each vertical bar represents an individual patient on study. Height of the bar represents time on therapy, and color represents Response Evaluation Criteria in Solid Tumors response. PR, partial response; SD, stable disease; PD, progressive disease. Journal of Thoracic Oncology 2013 8, DOI: ( /JTO.0b013e31828c3950) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Progression-free survival. Kaplan–Meier curves of progression-free survival by study arm are shown. HR, hazard ratio. Journal of Thoracic Oncology 2013 8, DOI: ( /JTO.0b013e31828c3950) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Overall survival. Kaplan–Meier curves of progression-free survival by study arm are shown. HR, hazard ratio. Journal of Thoracic Oncology 2013 8, DOI: ( /JTO.0b013e31828c3950) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

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