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Figure 1 Sections of muscle biopsy specimens stained with hematoxylin & eosin (HE)
Sections of muscle biopsy specimens stained with hematoxylin & eosin (HE) Classic aDM (A, B) with characteristic perifascicular atrophy. B-cell–rich (C, D) and follicle-like aDM (E, F) with dense lymphocytic aggregates and jDM (G, H) with demarcated infarction of small muscle fascicles with focal loss of normal microarchitecture (scattered line). Internalized myonuclei (B, F, arrowheads), myophagocytosis (D, arrowhead), and the presence of nonrimmed vacuoles (G, arrowhead) were seen in all muscle specimens but were more often detected in B-cell–rich and follicle-like aDM and in jDM. aDM = adult dermatomyositis; jDM = juvenile dermatomyositis. Josefine Radke et al. Neurol Neuroimmunol Neuroinflamm 2018;5:e451 Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.
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