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What Does the Future Hold and What Will It Mean for Patients?
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The Standard of Care is Changing Again
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Why Do We Need a New Standard of Care?
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The Ideal Treatment for Chronic HCV Infection
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Agents in Phase 3 HCV Treatment Pipeline Not Approved for Use in the US
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Sofosbuvir
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VALENCE: Sofosbuvir + RBV for 24 Weeks in G3 HCV Infection
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NEUTRINO Study: SVR12 by HCV Genotype
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NEUTRINO Study: Virologic Response by Cirrhosis Status
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Simeprevir in Patients With G1 HCV Infection
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Shortened Therapy in 85% to 91%
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Q80K: A Major Issue
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On the Road to IFN-free Therapy
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On the Road to IFN-free Therapy (cont)
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One Size Fits All vs Tailored Regimen
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Second-Generation Protease Inhibitor-based, IFN-free Regimens
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PI + NS5A in Prior Null Responders
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IFN-free Regimens Combining 3 DAA Drug Classes
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More Potent Protease Inhibitors in Phase 2 Clinical Trials
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What Does It Mean for Patients?
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Abbreviations
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Abbreviations (cont)
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References
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References (cont)
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References (cont)
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