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RalGDS comes of age Cancer Cell

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1 RalGDS comes of age Cancer Cell
Pablo Rodriguez-Viciana, Frank McCormick  Cancer Cell  Volume 7, Issue 3, Pages (March 2005) DOI: /j.ccr Copyright © 2005 Elsevier Inc. Terms and Conditions

2 Figure 1 Pathways downstream of Ras
Members of the Ras family bind and activate multiple downstream effectors. Binding is GTP-dependent and engages the highly conserved effector binding region of Ras and its close relatives. Direct activating events are shown in black arrows, trasncriptional events in green. This figure is greatly oversimplified, but ilustrates the complexity of downstream signaling and the fact that downstream pathways are entangled at many levels. Cancer Cell 2005 7, DOI: ( /j.ccr ) Copyright © 2005 Elsevier Inc. Terms and Conditions

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