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Automated categorization of methicillin-resistant Staphylococcus aureus clinical isolates into different clonal complexes by MALDI-TOF mass spectrometry 

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Presentation on theme: "Automated categorization of methicillin-resistant Staphylococcus aureus clinical isolates into different clonal complexes by MALDI-TOF mass spectrometry "— Presentation transcript:

1 Automated categorization of methicillin-resistant Staphylococcus aureus clinical isolates into different clonal complexes by MALDI-TOF mass spectrometry  M. Camoez, J.M. Sierra, M.A. Dominguez, M. Ferrer-Navarro, J. Vila, I. Roca  Clinical Microbiology and Infection  Volume 22, Issue 2, Pages 161.e1-161.e7 (February 2016) DOI: /j.cmi Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Averaged spectra plots showing the presence or absence of the relevant peak biomarkers for matrix-assisted laser desorption ionization time-of-flight mass spectrometry discrimination of the four main methicillin-resistant Staphylococcus aureus clonal complexes in the supervised neural network model. CC5 (red), CC8 (green), CC22 (blue); CC398 (yellow). x-axis shows the mass per charge ratio values (m/z) and y-axis indicates the intensities of peaks expressed in arbitrary intensity units. Clinical Microbiology and Infection  , 161.e1-161.e7DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Two-dimensional peak distribution diagrams displaying the paired distribution for the best separating peaks in the supervised neural network model; the ellipses represent the standard deviation of the class average of the peak areas/intensities. CC5 (red), CC8 (green), CC22 (blue); CC398 (yellow). The peak numbers and m/z values are indicated on the x- and y-axes, respectively. Clinical Microbiology and Infection  , 161.e1-161.e7DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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