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Abdominal Adiposity and Insulin Resistance in Early Pregnancy

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1 Abdominal Adiposity and Insulin Resistance in Early Pregnancy
Leanne R. De Souza, MSc, Eva Kogan, MD, Howard Berger, MD, João G. Alves, MD, PhD, Gerald Lebovic, PhD, Ravi Retnakaran, MD, MSc, Jonathon L. Maguire, MD, MSc, Joel G. Ray, MD, MSc  Journal of Obstetrics and Gynaecology Canada   Volume 36, Issue 11, Pages (November 2014) DOI: /S (15) Copyright © 2014 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

2 Forest plot comparing variance (adjusted r2, 95% CI) for different measures of maternal obesity in early pregnancy and their association with insulin resistance. Obesity measures included pre-pregnancy BMI, BMI at 11 to 14weeks’ gestation, as well as subcutaneous, visceral and total adipose tissue depth at 11 to 14weeks’ gestation. Insulin resistance was determined at 16 to 22weeks’ gestation using the HOMA-IR or the ISI after a two-hour 75-gram oral glucose tolerance test. Measures of BMI were adjusted for maternal age, parity, and ethnicity. Measures of adipose tissue depth were adjusted for maternal age, parity, ethnicity, and pre-pregnancy BMI. Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2014 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions


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