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Behaviour of spectral entropy, spectral edge frequency 90%, and alpha and beta power parameters during low-dose propofol infusion  P. Mahon, B.R. Greene,

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Presentation on theme: "Behaviour of spectral entropy, spectral edge frequency 90%, and alpha and beta power parameters during low-dose propofol infusion  P. Mahon, B.R. Greene,"— Presentation transcript:

1 Behaviour of spectral entropy, spectral edge frequency 90%, and alpha and beta power parameters during low-dose propofol infusion  P. Mahon, B.R. Greene, C. Greene, G.B. Boylan, G.D. Shorten  British Journal of Anaesthesia  Volume 101, Issue 2, Pages (August 2008) DOI: /bja/aen161 Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 International 10–20 electrode positions. Block arrows show the bipolar montages used for comparison. British Journal of Anaesthesia  , DOI: ( /bja/aen161) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 (a) Relative beta power vs propofol target effect-site concentration in each of the six individual bipolar channels averaged across all patients over the frequency range 0.5–47 Hz. Values shown at each effect-site concentration are mean (standard error), averaged across all patients. (b) Spectral edge frequency 90 (SEF 90) vs propofol target effect-site concentration in each of the six individual bipolar channels for the frequency range 0.5–47 Hz. The effect was significant in channels: Fp1–Fp2, F4–C4, and F3–C3. Values shown at each effect-site concentration are mean (standard error), averaged across all patients. (c) Spectral entropy (Hs) vs propofol target effect-site concentration in each of the six individual bipolar channels for the frequency range 0.5–47 Hz. Values shown at each effect-site concentration are mean (standard error), averaged across all patients. The effect was significant in all channels. British Journal of Anaesthesia  , DOI: ( /bja/aen161) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 Three-dimensional power spectral density (PSD) function from Patient 11: (a) fronto-central channel F4–C4 and (b) the occipito-parietal channel P3–O1. The time axis corresponds to propofol effect-site concentration 0.5–2 μg ml−1 (increased in 4 min increments). High frequency activity is a clear feature resulting in a broad power spectrum demonstrating a leftward shift as high frequency (beta) activity increases with increasing effect-site concentration. British Journal of Anaesthesia  , DOI: ( /bja/aen161) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

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