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Rapid acquisition of decreased carbapenem susceptibility in a strain of Klebsiella pneumoniae arising during meropenem therapy  J. Findlay, A. Hamouda,

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Presentation on theme: "Rapid acquisition of decreased carbapenem susceptibility in a strain of Klebsiella pneumoniae arising during meropenem therapy  J. Findlay, A. Hamouda,"— Presentation transcript:

1 Rapid acquisition of decreased carbapenem susceptibility in a strain of Klebsiella pneumoniae arising during meropenem therapy  J. Findlay, A. Hamouda, S.J. Dancer, S.G.B. Amyes  Clinical Microbiology and Infection  Volume 18, Issue 2, Pages (February 2012) DOI: /j x Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

2 FIG. 1 The pulsed-field typing of K1 and K2 after digestion with XbaI.
Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

3 FIG. 2 A section of an SDS PAGE gel showing the major OMPs in K1, K2, ATCC 13883, MGH78578, an MGH78578 meropenem mutant and a K1 meropenem mutant. NB, nutrient broth; LB, Luria-Bertani broth. Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

4 FIG. 3 The expression of the selected genes in K1, K2 and ATCC NB, nutrient broth; LB, Luria-Bertani broth. Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions


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