1. Enhanced Anti-Mycobacterial Immunity in Children with Erythema Nodosum and a Positive Tuberculin Skin Test 
Mark P. Nicol, Beate Kampmann, Patricia Lawrence, Kathy Wood, Sandy Pienaar, David Pienaar, Brian Eley, Michael Levin, David Beatty, Suzanne T.B. Anderson 
Journal of Investigative Dermatology 
Volume 127, Issue 9, Pages (September 2007)
DOI: /sj.jid
Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

2. Figure 1
Age distribution of children with EN, children with acute PTB and healthy TST+ children. Lines represent median values. Children with TST+ EN fell into two distinct age groups.
Journal of Investigative Dermatology  , DOI: ( /sj.jid )
Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

3. Figure 2
Cytokine responses (a: IFNγ, b: TNF, c: IL12p70, d: IL-10) in whole blood by category. Diluted whole blood was stimulated with PPD (for measurement of IFNγ and IL-10), with LPS (TNF measurement) or LPS plus IFNγ (IL-12p70). Cytokines in culture supernatants were measured by ELISA in children with EN, acute PTB or healthy TST+ children. Plots show median values with quartiles. Whiskers show highest and lowest values. Blood from children with EN produced significantly more IFNγ in response to PPD than healthy TST+ children or children with PTB.
Journal of Investigative Dermatology  , DOI: ( /sj.jid )
Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

4. Figure 3
BCG lux GRs by category. Diluted whole blood was incubated with BCG lux for 96hours and the GR calculated using the formula: luminescence at 96hours/luminescence at 0 hour. Children with EN, acute PTB and healthy TST+children. Lines represent median values. Blood from children with EN restricted the growth of BCG lux significantly more than healthy TST+ children or children with PTB.
Journal of Investigative Dermatology  , DOI: ( /sj.jid )
Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions