1. Volume 14, Issue 3, Pages 195-204 (December 2007)
Mitochondrial energy conversion disturbance with decrease in ATP production as a source of systemic arterial hypertension 
Yuvenalii V. Postnov, Sergei N. Orlov, Yegor Y. Budnikov, Alexander D. Doroschuk, Anton Y. Postnov 
Pathophysiology 
Volume 14, Issue 3, Pages (December 2007)
DOI: /j.pathophys
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2. Fig. 1
Major systems involved in oxidative phosphorylation and Ca2+ transport in mitochondria. Abbreviations: IMM, inner mitochondrial membrane; PM, plasma membrane; I-IV, complexes providing electron (e−) transport from NADH to O2; 1, mitochondrial ATP synthase (F1Fo-ATPase); 2, adenine nucleotide translocase; 3, phosphate carrier; 4, Ca2+ uniporter; 5 and 6, Ca2+/Na+ and Ca2+/H+ antiporters, respectively; 7, mitochondrial permeability transition (MPT) pore; 8 and 9, Ca2+-ATPase and Na+, K+-ATPAse, respectively. Factors involved in activation (+) and inhibition (−) of MPT are shown by broken arrows. For more details, see the text. Note that the scheme does not reflect the relative locations of membrane proteins.
Pathophysiology  , DOI: ( /j.pathophys )
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3. Fig. 2
Rate of ATP synthesis in isolated mitochondria from the liver and brain of SHR and WKY rats measured in Ca2+-free medium. Mean values obtained in mitochondria from WKY were taken as 100%. *p<0.01. For more details, see [22,23].
Pathophysiology  , DOI: ( /j.pathophys )
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4. Fig. 3
Dependence of Ca2+ uptake by isolated mitochondria from the heart, adipose tissue and brain of WKY and SHR on free Ca2+ concentration. For more details, see [26–28].
Pathophysiology  , DOI: ( /j.pathophys )
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5. Fig. 4
Dependence of the ATP synthesis rate by mitochondria isolated from SHR and WKY rat livers on free Ca2+ concentration. For more details, see [26–28].
Pathophysiology  , DOI: ( /j.pathophys )
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6. Fig. 5
Kinetics of Ca2+-induced Ca2+ release in mitochondria isolated from SHR and WKY rat livers. Abbreviations: V1, rate of calcium uptake by mitochondria; Cmin-SHR, Cmin-WKY, minimal values of Ca2+ concentrations in the incubation medium; V2-SHR, V2-WKY, rates of Ca2+ release from mitochondria; tSHR, tWKY, times of cycle duration; M, addition of mitochondria into incubation medium containing free [Ca2+] at the initial concentration of 55μM. For more details, see [59].
Pathophysiology  , DOI: ( /j.pathophys )
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7. Fig. 6
Scheme showing possible mechanisms of the involvement of abnormal mitochondrial function in the pathogenesis of hypertension.
Pathophysiology  , DOI: ( /j.pathophys )
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