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Published bySeweryna Szydłowska Modified over 5 years ago
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Unlocking Collagen Proteolysis with a Gentle Pull
Laurent Kreplak, Andrew D. Rutenberg Biophysical Journal Volume 114, Issue 3, Pages (February 2018) DOI: /j.bpj Copyright © 2017 Biophysical Society Terms and Conditions
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Figure 1 Centrifuge force microscopy coupled with careful surface chemistry to achieve single-molecule collagen-tethering (A) opens the road for proteolytic assays under constant force. In the case of collagen-III (B), this assay demonstrates force-induced proteolytic activity of trypsin (2). To see this figure in color, go online. Biophysical Journal , DOI: ( /j.bpj ) Copyright © 2017 Biophysical Society Terms and Conditions
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