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Application of Nuclear Magnetic Resonance to Detect Toxigenic Clostridium difficile from Stool Specimens  Paul Yang, Sara Hash, Katherine Park, Charlene.

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Presentation on theme: "Application of Nuclear Magnetic Resonance to Detect Toxigenic Clostridium difficile from Stool Specimens  Paul Yang, Sara Hash, Katherine Park, Charlene."— Presentation transcript:

1 Application of Nuclear Magnetic Resonance to Detect Toxigenic Clostridium difficile from Stool Specimens  Paul Yang, Sara Hash, Katherine Park, Charlene Wong, Loganathan Doraisamy, Jonas Petterson, Cathy A. Petti, Pamela M. Ward, Seung Heon Lee, Suresh Menon, Rosemary C. She  The Journal of Molecular Diagnostics  Volume 19, Issue 2, Pages (March 2017) DOI: /j.jmoldx Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

2 Figure 1 T2 signal change values for concentrations of toxigenic Clostridium difficile used to assess analytical sensitivity. A T2 signal change cut-off value of >100 ms was determined empirically to distinguish positive from negative test results. CFU, colony forming units. The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx ) Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

3 Figure 2 Receiver operating characteristics curve for the M100 Clostridium difficile assay based on results of 115 clinical samples compared with the Xpert C. difficile/Epi PCR assay. Area under the curve, 0.922. The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx ) Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions


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