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Does moderate hypothermia really carry less bleeding risk than deep hypothermia for circulatory arrest? A propensity-matched comparison in hemiarch replacement 

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Presentation on theme: "Does moderate hypothermia really carry less bleeding risk than deep hypothermia for circulatory arrest? A propensity-matched comparison in hemiarch replacement "— Presentation transcript:

1 Does moderate hypothermia really carry less bleeding risk than deep hypothermia for circulatory arrest? A propensity-matched comparison in hemiarch replacement  Jeffrey E. Keenan, MD, Hanghang Wang, MD, Brian C. Gulack, MD, Asvin M. Ganapathi, MD, Nicholas D. Andersen, MD, Brian R. Englum, MD, MHS, Yamini Krishnamurthy, BS, Jerrold H. Levy, MD, Ian J. Welsby, MBBS, G. Chad Hughes, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 152, Issue 6, Pages e2 (December 2016) DOI: /j.jtcvs Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 A, Bar graph demonstrating the number of cases of hemiarch replacement per year from the total cohort with either deep (orange) or moderate (green) hypothermic circulatory arrest. Only patients up to August 2014 are included in that year. B, Bar graph demonstrating the number of cases of hemiarch replacement per year after propensity matching with either deep (orange) or moderate (green) hypothermic circulatory arrest. Only patients up to August 2014 are included in that year. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

3 Figure E1 Institutional transfusion algorithm schematic. CPB, Cardiopulmonary bypass; FFP, fresh-frozen plasma; TEG, thromboelastogram; HCA, hypothermic circulatory arrest; rFVIIa, recombinant activated Factor VII; PRBC, packed red blood cells; ICU, intensive care unit. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

4 Figure E2 Standardized differences between the DHCA and MHCA groups before and after matching. DHCA, Deep hypothermic circulatory arrest; MHCA, moderate hypothermic circulatory arrest. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

5 Comparing the effect of deep versus moderate hypothermic circulatory arrest on bleeding.
The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

6 The Journal of Thoracic and Cardiovascular Surgery 2016 152, 1559-1569
The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

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