1. Endoplasmic reticulum (ER) stress inhibits IGF-1 function in articular cartilage 
R.R. Yammani, J. Haywood, R.F. Loeser 
Osteoarthritis and Cartilage 
Volume 24, Pages S180-S181 (April 2016)
DOI: /j.joca
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2. Fig 1. Thapsigargin (TG) induces CHOP (ER stress) expression in human articular chondrocytes. Data presented is representative of 3 independent experiments.
Osteoarthritis and Cartilage  , S180-S181DOI: ( /j.joca )
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3. Fig 2. ER stress inhibits IGF-1 function
Fig 2. ER stress inhibits IGF-1 function. Chondrocytes were pretreated with or without 500uM PBA or 2uM TG for 24 followed by A, 50ng/ml IGF-1 for 30 minutes for signaling studies or B, 100ng/ml IGF-1 overnight for PG synthesis. Data presented is representative of 3 independent experiments.
Osteoarthritis and Cartilage  , S180-S181DOI: ( /j.joca )
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