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Tigecycline-induced inhibition of mitochondrial DNA translation may cause lethal mitochondrial dysfunction in humans  S.J. Vandecasteele, S. Seneca, J.

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Presentation on theme: "Tigecycline-induced inhibition of mitochondrial DNA translation may cause lethal mitochondrial dysfunction in humans  S.J. Vandecasteele, S. Seneca, J."— Presentation transcript:

1 Tigecycline-induced inhibition of mitochondrial DNA translation may cause lethal mitochondrial dysfunction in humans  S.J. Vandecasteele, S. Seneca, J. Smet, M. Reynders, J. De Ceulaer, A.V. Vanlander, R. van Coster  Clinical Microbiology and Infection  Volume 24, Issue 4, Pages 431.e1-431.e3 (April 2018) DOI: /j.cmi Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Treatment course and evolution of platelets and serum bicarbonate. Administration of tigecycline (100 mg daily) is represented as thick solid horizontal line and administration of bicarbonate as dotted horizontal line. On y-axis, evolution of platelets is indicated by solid line and serum bicarbonate by dotted line. Clinical Microbiology and Infection  , 431.e1-431.e3DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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