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The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review by Margaret Astin, Tom Griffin, Richard D Neal, Peter Rose,

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Presentation on theme: "The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review by Margaret Astin, Tom Griffin, Richard D Neal, Peter Rose,"— Presentation transcript:

1 The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review
by Margaret Astin, Tom Griffin, Richard D Neal, Peter Rose, and William Hamilton BJGP Volume 61(586):e231-e243 May 1, 2011 ©2011 by British Journal of General Practice

2 Positive predictive values of rectal bleeding in the diagnosis of colorectal cancer in primary care.
Positive predictive values of rectal bleeding in the diagnosis of colorectal cancer in primary care. Random effects pooled estimate (diamond) is based on a subgroup (B) aged ≥50 years. Margaret Astin et al. Br J Gen Pract 2011;61:e231-e243 ©2011 by British Journal of General Practice

3 Positive likelihood ratios (LRs) of rectal bleeding and another symptom:A, abdominal pain;Bweight loss; C, change in bowel habit. Positive likelihood ratios (LRs) of rectal bleeding and another symptom:A, abdominal pain;Bweight loss; C, change in bowel habit. Margaret Astin et al. Br J Gen Pract 2011;61:e231-e243 ©2011 by British Journal of General Practice

4 Methodological quality of studies.
Margaret Astin et al. Br J Gen Pract 2011;61:e231-e243 ©2011 by British Journal of General Practice

5 Diagram of information flow.
Margaret Astin et al. Br J Gen Pract 2011;61:e231-e243 ©2011 by British Journal of General Practice


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