1. The metallic silver sign with narrow-band imaging: a new endoscopic predictor for pharyngeal and esophageal neoplasia 
Roberta Maselli, MD, Haruhiro Inoue, MD, PhD, Haruo Ikeda, MD, Manabu Onimaru, MD, Akira Yoshida, MD, Esperanza Grace Santi, MD, Hiroki Sato, MD, Nicolas Eleftheriadis, MD, Bu'Hussain Hayee, MRCP, PhD, Shin-ei Kudo, MD, PhD 
Gastrointestinal Endoscopy 
Volume 78, Issue 3, Pages (September 2013)
DOI: /j.gie
Copyright © 2013 American Society for Gastrointestinal Endoscopy Terms and Conditions

2. Figure 1
A, 0-IIa lesion at the proximal esophagus seen on white light endoscopy. B, On chromoendoscopy with the use of Lugol's solution, the lesion avoids Lugol. C, 1 minute after exposure to Lugol's solution, the lesion develops a pink color. D, Silvery metallic appearance of lesion under NBI.
Gastrointestinal Endoscopy  , DOI: ( /j.gie )
Copyright © 2013 American Society for Gastrointestinal Endoscopy Terms and Conditions

3. Figure 2
0-IIb lesion involving two thirds of the thoracic esophageal circumference. A, The lesion appears to avoid Lugol 1 minute after spraying. B, Pink color sign. C, Metallic silver sign.
Gastrointestinal Endoscopy  , DOI: ( /j.gie )
Copyright © 2013 American Society for Gastrointestinal Endoscopy Terms and Conditions

4. Figure 3
0-IIb lesion in the thoracic esophagus. A, Immediately after Lugol solution dying. B, The lesion turns pink after 2 minutes. C, Metallic silver sign appears in the lesion under NBI.
Gastrointestinal Endoscopy  , DOI: ( /j.gie )
Copyright © 2013 American Society for Gastrointestinal Endoscopy Terms and Conditions