1. Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study 
Josephine M Bryant, BSc, Simon R Harris, PhD, Prof Julian Parkhill, PhD, Prof Rodney Dawson, MD, Prof Andreas H Diacon, MD, Prof Paul van Helden, PhD, Alex Pym, MD, Aziah A Mahayiddin, FRCP, Charoen Chuchottaworn, MD, Prof Ian M Sanne, MMed PhD, Cheryl Louw, MB, Martin J Boeree, MD, Prof Michael Hoelscher, FRCP, Prof Timothy D McHugh, PhD, Anna L C Bateson, PhD, Robert D Hunt, BSc, Solomon Mwaigwisya, MSc, Laura Wright, BSc, Prof Stephen H Gillespie, DSc, Stephen D Bentley, PhD 
The Lancet Respiratory Medicine 
Volume 1, Issue 10, Pages (December 2013)
DOI: /S (13)
Copyright © 2013 Bryant et al. Open Access article distributed under the terms of CC BY Terms and Conditions

2. Figure 1
Distribution of the case outcomes for study patients based on sequencing quality data, sequence comparison, and clinical evaluation
The Lancet Respiratory Medicine 2013 1, DOI: ( /S (13) )
Copyright © 2013 Bryant et al. Open Access article distributed under the terms of CC BY Terms and Conditions

3. Figure 2
Pair-wise distances between pairs of isolates from the same patient
For each patient pair, the calculated pair-wise distance is based on the number of high quality base differences between the samples.
The Lancet Respiratory Medicine 2013 1, DOI: ( /S (13) )
Copyright © 2013 Bryant et al. Open Access article distributed under the terms of CC BY Terms and Conditions

4. Figure 3
MIRU-VNTR loci differing between pairs of isolates from the same patient
(A) Number of loci differing between pairs of isolates from the same patient with relapse, re-infection, mixed infection, and single isolated positives identified by whole genome sequencing. (B) Comparison of differences detected by whole genome sequence data and MIRU-VNTR; red=relapse, blue=re-infection. MIRU-VNTR=mycobacterial interspersed repetitive unit-variable number of tandem repeat.
The Lancet Respiratory Medicine 2013 1, DOI: ( /S (13) )
Copyright © 2013 Bryant et al. Open Access article distributed under the terms of CC BY Terms and Conditions