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Inhaled nitric oxide, right ventricular efficiency, and pulmonary vascular mechanics: Selective vasodilation of small pulmonary vessels during hypoxic.

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Presentation on theme: "Inhaled nitric oxide, right ventricular efficiency, and pulmonary vascular mechanics: Selective vasodilation of small pulmonary vessels during hypoxic."— Presentation transcript:

1 Inhaled nitric oxide, right ventricular efficiency, and pulmonary vascular mechanics: Selective vasodilation of small pulmonary vessels during hypoxic pulmonary vasoconstriction  Neal D. Hillman, MDa, Ira M. Cheifetz, MDb, Damian M. Craig, MSa, Peter K. Smith, MDa, Ross M. Ungerleider, MDa, Jon N. Meliones, MD, FCCMb  The Journal of Thoracic and Cardiovascular Surgery  Volume 113, Issue 6, Pages (June 1997) DOI: /S (97)70285-X Copyright © 1997 Mosby, Inc. Terms and Conditions

2 Fig. 1 NO resulted in a decrease of pulmonary artery (Pa) pressure. *p < 0.05 versus 0 ppm. Pre, Before NO; Post, after NO. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97)70285-X) Copyright © 1997 Mosby, Inc. Terms and Conditions

3 Fig. 2 Total RV power output diminished during NO administration and reached significance at 80 ppm. *p < 0.05 versus 0 ppm. Pre, Before NO; Post, after NO. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97)70285-X) Copyright © 1997 Mosby, Inc. Terms and Conditions

4 Fig. 3 NO administration significantly improved transpulmonary vascular efficiency (TVE) (pulmonary blood flow/total RV power). *p < 0.05 versus 0 ppm. Pre, Before NO; Post, after NO. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97)70285-X) Copyright © 1997 Mosby, Inc. Terms and Conditions


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