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Non–hepatitis virus associated mixed essential cryoglobulinemia

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Presentation on theme: "Non–hepatitis virus associated mixed essential cryoglobulinemia"— Presentation transcript:

1 Non–hepatitis virus associated mixed essential cryoglobulinemia
Nicholas M.P. Annear, H. Terence Cook, Mark Atkins, Charles D. Pusey, Alan D. Salama  Kidney International  Volume 77, Issue 2, Pages (January 2010) DOI: /ki Copyright © 2010 International Society of Nephrology Terms and Conditions

2 Figure 1 Renal biopsy taken at the time of presentation after treatment of the urinary tract infection. (a) Glomerulus showing global hypercellularity (hematoxylin and eosin staining (H&E)). (b) Periodic acid-Schiff stain highlights the presence of mononuclear cells within capillary lumens. (c) Artery showing fibrinoid necrosis (H&E); original magnification × 400 Kidney International  , DOI: ( /ki ) Copyright © 2010 International Society of Nephrology Terms and Conditions

3 Figure 2 Biochemical and serological response to therapy. The improvement in serum creatinine, reduction in cryoglobulin levels, and increase in circulating C4 are all shown. These changes have persisted despite subsequent reconstitution of her circulating B cells. Kidney International  , DOI: ( /ki ) Copyright © 2010 International Society of Nephrology Terms and Conditions


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