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A 12-month multicenter, randomized study comparing the levonorgestrel intrauterine system with the etonogestrel subdermal implant  Dan Apter, M.D., Ph.D.,

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Presentation on theme: "A 12-month multicenter, randomized study comparing the levonorgestrel intrauterine system with the etonogestrel subdermal implant  Dan Apter, M.D., Ph.D.,"— Presentation transcript:

1 A 12-month multicenter, randomized study comparing the levonorgestrel intrauterine system with the etonogestrel subdermal implant  Dan Apter, M.D., Ph.D., Paula Briggs, M.B.Ch.B., Marjo Tuppurainen, M.D., Julia Grunert, M.Sc., Eeva Lukkari-Lax, M.D., Ph.D., Sarah Rybowski, M.B.B.S., Kristina Gemzell-Danielsson, M.D., Ph.D.  Fertility and Sterility  Volume 106, Issue 1, Pages e5 (July 2016) DOI: /j.fertnstert Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

2 Supplemental Figure 1 Disposition of women in the study. aModified intention-to-treat set: all women for whom at least one placement attempt was made. bFull analysis set: all women who had a successful placement/insertion. ENG = etonogestrel; LNG-IUS 8 = levonorgestrel intrauterine system total content 13.5 mg (average, ∼8 μg/24 hours during the first year). Fertility and Sterility  , e5DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

3 Supplemental Figure 2 Mean number of bleeding and spotting days by 90-day reference intervalsa (modified intention-to-treat setb) in the LNG-IUS 8 and ENG implant groups. aThe numbers of bleeding and spotting days were not recorded at baseline. bModified intention-to-treat set: all women for whom at least one placement/insertion attempt was made. ENG = etonogestrel; LNG-IUS 8 = levonorgestrel intrauterine system total content 13.5 mg (average, ∼8 μg/24 hours during the first year). Fertility and Sterility  , e5DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions


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