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Uterine viability in the baboon after ligation of uterine vasculature: a pilot study to assess alternative perfusion and venous return for uterine transplantation 

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Presentation on theme: "Uterine viability in the baboon after ligation of uterine vasculature: a pilot study to assess alternative perfusion and venous return for uterine transplantation "— Presentation transcript:

1 Uterine viability in the baboon after ligation of uterine vasculature: a pilot study to assess alternative perfusion and venous return for uterine transplantation  Marie Shockley, M.D., Katrin Arnolds, M.D., Benjamin Beran, M.D., Krishna Rivas, M.V., Pedro Escobar, M.D., Andreas Tzakis, M.D., Tommaso Falcone, M.D., Michael L. Sprague, M.D., Stephen Zimberg, M.D.  Fertility and Sterility  Volume 107, Issue 4, Pages (April 2017) DOI: /j.fertnstert Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 (A) Ligation of bilateral uterine veins. Surgical technique used on the first group of subjects (n = 3), notable for preservation of the uterine arteries. (B) In vivo uterus after ligation of bilateral uterine veins. Suture knots at uterine veins are visible. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 (A) Ligation of bilateral uterine veins and arteries. Surgical technique used on the second group of subjects (n = 3), notable for transection of bilateral uterine vessels. (B) In vivo uterus after ligation of bilateral uterine veins and arteries. Uterus remains suspended by the utero-ovarian attachments alone after bilateral uterine vessel ligation in a Papio hamadryas study subject. Image captured before reanastamosis of the cervix to the vaginal cuff. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Spy image of uterine perfusion after bilateral uterine vein ligation. The picture is oriented with the subject's feet to the left and the head to the right. The surgeon's index and middle finger are retracting the bladder, and a sterile lap is covering the omentum. The reference point (100%) is placed along the right pelvic sidewall. Comparison points have been placed over the uterine fundus (120%) and the cervico-vaginal anastomosis (62%). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions


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