Presentation is loading. Please wait.

Presentation is loading. Please wait.

Clinical profile of ceftobiprole, a novel β-lactam antibiotic

Similar presentations


Presentation on theme: "Clinical profile of ceftobiprole, a novel β-lactam antibiotic"— Presentation transcript:

1 Clinical profile of ceftobiprole, a novel β-lactam antibiotic
G.J. Noel  Clinical Microbiology and Infection  Volume 13, Pages (June 2007) DOI: /j x Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

2 FIG. 1 Crystal structure of ceftobiprole bound to the active site of Staphylococcus aureus penicillin-binding protein 2′. Courtesy of M. Page, Basilea Pharmaceutica Ltd, Basel, Switzerland. Clinical Microbiology and Infection  , 25-29DOI: ( /j x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

3 FIG. 2 Ceftobiprole activity against (a) Gram-positive (46th ICAAC, abstract E-116) and (b) Gram-negative (Enterobacteriaceae) isolates (15th ECCMID, abstract P-1569). CoNS MR, methicillin-resistant/coagulase-negative staphylococci; CoNS MS, methicillin-susceptible/coagulase-negative staphylococci; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-susceptible S. aureus. Clinical Microbiology and Infection  , 25-29DOI: ( /j x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

4 FIG. 3 AUC and Cmax of single ascending doses of ceftobiprole prodrug [3]. Clinical Microbiology and Infection  , 25-29DOI: ( /j x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions


Download ppt "Clinical profile of ceftobiprole, a novel β-lactam antibiotic"

Similar presentations


Ads by Google