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Colonic transit influences deoxycholic acid kinetics

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Presentation on theme: "Colonic transit influences deoxycholic acid kinetics"— Presentation transcript:

1 Colonic transit influences deoxycholic acid kinetics
Martin J. Veysey, Linzi A. Thomas, Anthony I. Mallet, Paul J. Jenkins, G.Michael Besser, Gerard M. Murphy, R.Hermon Dowling  Gastroenterology  Volume 121, Issue 4, Pages (October 2001) DOI: /gast Copyright © 2001 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Group and paired data for the DCA input rate in nonacromegalic control subjects, acromegalic patients untreated with octreotide (OT), acromegalic patients on long-term octreotide treatment (LTOT), and patients with constipation. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions

3 Fig. 2 Group and paired data for the DCA pool size in nonacromegalic control subjects, acromegalic patients untreated with octreotide (OT), acromegalic patients on long-term octreotide treatment (LTOT), and patients with constipation. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions

4 Fig. 3 Excess 13C-DCA, in the DCA pool, in acromegalic patients studied before and during octreotide treatment (n = 5). Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions

5 Fig. 4 Relationship between LBTT and (A) the DCA input rate and (B) the DCA pool size. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions

6 Fig. 5 Relationship between the input rate of DCA into the enterohepatic circulation and the proportion of DCA in fasting serum. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions


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