1. Figure 1 Mechanistic classification of lncRNAs
Figure 1 | Mechanistic classification of lncRNAs. a | Signal lncRNAs are transcribed with spatiotemporal precision and expressed in response to developmental cues, according to cellular context or diverse stimuli. b | Decoy lncRNAs regulate transcription by titrating away transcription factors and other proteins from chromatin without exerting any additional functions. c | Guide lncRNAs bind ribonucleoprotein complexes and direct them to chromatin and other specific targets. d | Scaffold lncRNAs interact with multiple partners to form a chromatin modifying complex that either represses or activates transcription.
Lorenzen, J. M. & Thum, T. (2016) Long noncoding RNAs in kidney and cardiovascular diseases
Nat. Rev. Nephrol. doi: /nrneph