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Volume 64, Issue 3, Pages (September 2003)

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Presentation on theme: "Volume 64, Issue 3, Pages (September 2003)"— Presentation transcript:

1 Volume 64, Issue 3, Pages 801-807 (September 2003)
Fabry disease: Detection of undiagnosed hemodialysis patients and identification of a “renal variant” phenotype1  Shoichiro Nakao, Chihaya Kodama, Toshihiro Takenaka, Akihiro Tanaka, Yuichiro Yasumoto, Aichi Yoshida, Tamotsu Kanzaki, Annette L.D. Enriquez, Christine M. Eng, Hiromitsu Tanaka, Chuwa Tei, Robert J. Desnick  Kidney International  Volume 64, Issue 3, Pages (September 2003) DOI: /j x Copyright © 2003 International Society of Nephrology Terms and Conditions

2 Figure 1 Plasma α-galactosidase A (α-Gal A) activity in 89 normal healthy males and 514 males with end-stage renal disease (ESRD) on hemodialysis. See accompanying text for details. Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions

3 Figure 2 Photomicrograph of a renal biopsy from patient 6. (A) Fixation of the original specimen in osmium and staining with toluidine blue O revealed the glycosphingolipid deposits in the epithelial cells and in the capillary endothelial cells as observed by light microscopy (×780). (B) Electron photomicrograph of a uranyl acetate and lead citrate stained ultrathin section showed stacked or concentric lamellar inclusions, and/or solid opaque material in the epithelial and endothelial cells (bar indicates 3 nm). Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions


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