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Coiled Bodies and Gems: Janus or Gemini?

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Presentation on theme: "Coiled Bodies and Gems: Janus or Gemini?"— Presentation transcript:

1 Coiled Bodies and Gems: Janus or Gemini?
A. Gregory Matera, Mark R. Frey  The American Journal of Human Genetics  Volume 63, Issue 2, Pages (August 1998) DOI: /301992 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

2 Figure 1 CBs and gems colocalize in most interphase cell types. HeLa-ATCC cells were fixed without detergent preextraction and then stained with anti-p80 coilin (coiled bodies are red) and anti-SMN (gems are green) antibodies. The twin structures in this cell type show complete overlap, as revealed by the yellow signal. Another strain of HeLa (HeLa-PV; Liu et al. 1996, 1997) often displays separate SMN and/or coilin foci (see text). In addition to the nuclear gem/CB staining, the SMN antibody localizes to the cytoplasm. The American Journal of Human Genetics  , DOI: ( /301992) Copyright © 1998 The American Society of Human Genetics Terms and Conditions


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